Active Protein Kinase B Regulates TCR
نویسندگان
چکیده
منابع مشابه
Negative regulation of mTOR activation by diacylglycerol kinases.
The engagement of TCR induces T-cell activation, which initiates multiple characteristic changes such as increase in cell size, cell division, and the production of cytokines and other effector molecules. The mammalian target of rapamycin (mTOR) regulates protein synthesis, transcription, cell survival, and autophagy. Critical roles of mTOR in T-cell activation and effector/memory differentiati...
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